[bip] biology-in-python Digest, Vol 1, Issue 2

Titus Brown titus at caltech.edu
Fri Aug 3 22:45:53 PDT 2007


-> I am looking a python library/app to predict transcription factors  
-> binding sites in human.
-> Does anyone know a good one?

Hey Olivier,

sorry, this got lost in all the traffic about formats and bad
programming ;).

The short answer: no.

The longer answer: there are a lot of frameworks out there, but none of
them work terribly well in large genomes, AFAIK.  Are you familiar with
the benchmark paper,

Assessing computational tools for the discovery of transcription
factor binding sites.  Nat Biotechnol. 2005 Jan;23(1):137-44.
PMID: 15637633

?

cheers,
--titus



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