[pygr-notify] [pygr commit] r81 - wiki

[codesite-noreply at google.com]

Author: ramccreary
Date: Tue Jul 22 13:14:58 2008
New Revision: 81

Modified:
   wiki/SearchingforPatterns.wiki

Log:
Edited wiki page through web user interface.

Modified: wiki/SearchingforPatterns.wiki
==============================================================================
--- wiki/SearchingforPatterns.wiki	(original)
+++ wiki/SearchingforPatterns.wiki	Tue Jul 22 13:14:58 2008
@@ -2,7 +2,7 @@

 = Introduction =

-This is a continuation of the article GenomeCalculationsUsingpygr (for 
the full code, see article). By demonstrating
+This is a continuation of the article GenomeCalculationsUsingpygr (for 
the full code, see article). By quantifying the trinucleotide repeats 
found in the E. coli genome, as well as the number of repeats per gene, 
the underlying organizational structure of the genome sequence can be 
further studied.


 = A Rundown of the Code =
@@ -50,6 +50,8 @@
 }}}

 = Potential Future Uses =
+
+By demonstrating simple ways to manipulate the data stored in the 
various containers available in pygr, more sophisticated uses for the 
data can be developed. For example, multiple human diseases, including 
Huntington's, Kennedy disease, or Fragile X syndrome, are caused by 
trinucleotide repeat expansion disorders. If a "normal" genome or gene 
is compared with a potentially mutated or diseased one, the counts of 
the various codons could show an excess of a particular codon, an 
altered reading frame (which would potentially change the number of 
each codon for the entire gene), or multiple other mutations.

 = Note =