[metagenomics-jclub] Reminder - Journal club tomorrow at 9:30am

[Ederson Jesus]

Hello everyone,

Since the paper that Tracy chose for discussion addresses the use of  
unifrac for data analysis, I thought that the paper attached (Schloss,  
2008) could be useful for the discussion. It recommends not to use the  
unifrac distance for clustering and ordination, but I think that this  
aspect should be further discussed. I like the idea of using unifrac  
because I think that it is an elegant method and because it precludes  
the use of cutoffs, but the phylogenies with 454 (at least with FLX  
sequences) does not look good to me. If they do not display good  
phylogenetic information, I wonder how good are the analysis results  
when using these phylogenies for community analysis. I saw that the  
Hamady and Knight (2009) addresses this topic too. Anyway, Rob  
Knight's group has been obtaining very good results with unifrac and I  
just would like to add just one piece of information about the  
subject. Maybe you can bring some interesting ideas. Unfortunately, I  
will not be present, since I will be in Pittsburgh until Thursday. So  
I will look forward to learn about what you discussed when I am back.

See you in the next round.

Cheers,

Ederson
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On Nov 3, 2009, at 3:23 PM, Tracy K. Teal wrote:

> Just a reminder that there's a microbial metagenomics journal club
> tomorrow at 9:30am in Plant and Soil Sciences Bldg, Rm 271, where  
> we'll be
> discussing:
>
> "Microbial community profiling for human microbiome projects: Tools,
> techniques and challenges"
> M. Hamandy and R. Knight
>
> Hope to see you there!
>
> -Tracy
>
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>