[khmer] digital normalization

C. Titus Brown ctb at msu.edu
Thu Jun 27 09:18:18 PDT 2013


Hi Yvan,

exactly correct.  You won't get identical results, but they should be
very similar.

cheers,
--titus

On Thu, Jun 27, 2013 at 03:59:14PM +0200, Yvan Wenger wrote:
> Dear Titus,
> 
> May I ask you a question?
> 
> I??have 1.3 billion illumina reads from 42 libraries (mRNA-seq). In
> theory, is it correct that I??would obtain similar results doing the
> digital normalization on the 1.3 billion reads than on performing it
> on each library first, and then perform a second round on all the
> remaining reads ?
> 
> This would somehow parallelize the process and greatly decrease the
> time required for this step...
> 
> Best regards,
> 
> Yvan Wenger
> PhD student

-- 
C. Titus Brown, ctb at msu.edu




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